from
Life ascending by Nick Lane (Norton, 2009)
The
chances are we will never live forever, nor would many wish to. The
problem is implicit in the make-up of the first colonies, the
distinction between the sex cells and the body. Once cells began to
differentiate, the disposable soma become subservient to the
germ-line. The more that cells become specialized, the greater the
benefits to the body as a whole, and so the germ-line in particular.
The most specialized cells of all are the neurons of the human
brain. Unlike more mundane cells, neurons are practically
irreplaceable, each one wired up with as many as ten thousand
synaptic connections, each synapse founded in our own unique
experience. Our brains are not replaceable. When one neuron die,
there is usually no pool of stem cells to replace them; and if one
day we succeed in engineering a pool of neuronal stem cells, we must
surely replace our own experience in the bargain. And so the price
of immortality is our humanity. |
amino
acids: the building blocks
that are linked in chains to form proteins in all living things.
Twenty different types are found in proteins; the order in which
they are linked together is specified by the DNA code.
DNA (deoxyribonucleic acid):
genetic material of all cells, twisted into double helix. The
sequence of four ‘letters’, A (adenine), T (thymine), C
(cytosine), and G (guanine) encodes the order of amino-acid building
blocks in proteins.
eukaryote: organism with cells
having a ‘true nucleus’. Eukaryotes comprise one of the three
domains of life. Animals, plants, fungi, algae and protozoa are
eukaryotes.
germ line: the cells
responsible for passing genes on to the next generation.
gene: unit of DNA
comprising the coding sequence for a single protein ( or RNA
molecule)
mitosis: type of cell division
in eukaryotic cells in which the chromosomes are doubled and then
separated to produce two daughter cells genetically identical to the
parent cell.
nucleus: central ‘control
centre’ of eukaryotic cells, containing genetic material (DNA)
combined with proteins, separated from the rest of the cell by a
double membrane.
protein: large molecule made
of a long chain of amino acids folded into a three-dimensional shape
that dictates its function. Cells make many different kinds of
proteins, which make up most of cell’s structure and carry out all
its functions. The amino acid sequence of proteins are encoded in
the genes.
RNA (ribonucleic acid):
single-stranded thread of nucleic acids, which resembles DNA in its
sequence of ‘letters’. There are various types of RNA (messenger
RNA, ribosomal RNA, and transfer RNA), which are all essential to
cells.
soma: the body, as opposed to
the germ line (the sex cells)
stem cell: unspecialized
progenitor cell, which divides by mitosis to replenish population of
specialized (differentiated) cells.
synapse: a region where nerve
cells join, a region where nerve impulses are transmitted and
received. |